The vast majority of our cosmetic clinical trials are substantiated in vivo. In vivo means that test products are tested or applied onto human volunteers and various assessments, observations and instrumental measurements are taken over specific time intervals. These human volunteers are compensated to cover the costs of their participation in a specific clinical trial. Healthy male and female volunteers between the ages 18 to 65 are eligible (subject to specific inclusion and exclusion criteria for each clinical trial) to participate in the various clinical studies. Volunteer inclusion and exclusion criteria may differ for each clinical study protocol as well as the specific study objectives.