Skin Barrier Function Assessment

This test method is utilised to evaluate the ability of a skin care product to prevent water loss in the stratum cornea, the epidermal layer of human skin, by measurement of water loss. Trans epidermal water loss (TEWL) measurement is utilised to substantiate this claim via instrumental analysis.

The measurement of the TEWL and the quality of the barrier function of the skin is the basic measurement for all cosmetic applications. Water is constantly evaporating from the skin, which is part of the body’s metabolism. As soon as the barrier function of the skin however is slightly damaged, the water loss will increase (even with smallest damages invisible to the human eye). Its measurement is an important parameter for the evaluation of the water barrier function of the skin and a basic measurement in all kinds of applications for topical applied products. Inside the probe of the instrument in a hollow cylinder, there are sensors to measure relative humidity and temperature. The probe measures the density gradient of the water evaporation from the skin Δc which is proportional to the TEWL. The amount of water loss (TEWL) is expressed in g/h/m².

The Indispensable instrument for formulation, claim support and efficacy & safety testing of skin care, household product, raw materials, and pharmaceutical products.  Further application in occupational health for the measurement of the skin barrier function can measure the necessity for using skin protection products, like hand sanitisers.

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